New carbohydrazide derivatives of 1H-pyrazolo[3,4-b]pyridine and trypanocidal activity
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چکیده
منابع مشابه
New carbohydrazide derivatives of 1H-pyrazolo[3,4-b]pyridine and trypanocidal activity.
This paper reports the in vitro trypanocidal activity evaluation of new carbohydrazide derivatives from 3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine, substituted at C-6 position by phenyl, methyl or trifluoromethyl group. These compounds were evaluated in order to identify the antiparasitic profile against trypomastigote and amastigote forms of Trypanosoma cruzi. The 4-carbohydrazide derivative...
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1CIQUP/Department of Chemistry and Biochemistry, Faculty of Sciences, University of Porto, Rua Campo Alegre 687, 4169-007 Porto, Portugal 2Department of Inorganic and Analytical Chemistry, Faculty of Chemical and Pharmaceutical Science, University of Chile, Casilla 233, Santiago, Chile 3Departamento of Molecular and Clinical Pharmacology, Faculty of Medicine, University of Chile, Santiago, Chil...
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ژورنال
عنوان ژورنال: Anais da Academia Brasileira de Ciências
سال: 2016
ISSN: 1678-2690,0001-3765
DOI: 10.1590/0001-3765201620160087